Cell Cycle Browser

Download a zip file containing all datasets and models:

All datasets included in the download:

u2os_cdt1_gemenin.csv FUCCI Live Cell Data:U2OS ES-FUCCI together with PCNA and calculated phase vector which results in 4 vectors for each cell
u2os_53bp1_pcna.csv U20S Data 1:U2OS cells expressing 53BP1-mVenus and PCNA-mCherry reporters
rpe_53bp1_pcna.csv RPE-1 Cell Line Data:RPE-1 cells expressing 53BP1-mVenus and PCNA-mCherry reporters
h9_oct4.csv H9/OCT4-mCherry live-cell data:Data for 20 H9 hESCs with an OCT4-mCherry reporter
u2os_cdt1.csv U2OS/Cdt1-mVenus:U2OS/Cdt1 data from Coleman et al, 2015
mcf10_cdk2emerg_20cells.csv MCF-10A CDK2 emerg early:Single-cell traces for 53BP1 and DHB-mVenus from Arora et al., 2017
mcf10_cdk2inc_20cells.csv MCF-10A CDK2 inc:Single-cell traces for 53BP1 and DHB-mVenus from Arora et al., 2017
mcf10_cdk2low_20cells.csv MCF-10A CDK2 emerg late:Single-cell traces for 53BP1 and DHB-mVenus from Arora et al., 2017
rpehtert_cdk2emerg_20cells.csv RPE-hTERT emerg early:Single-cell traces for 53BP1 and DHB-mVenus from Arora et al., 2017
rpehtert_cdk2inc_20cells.csv RPE-hTERT inc:Single-cell traces for 53BP1 and DHB-mVenus from Arora et al., 2017
rpehtert_cdk2low_20cells.csv RPE-hTERT emerg late:Single-cell traces for 53BP1 and DHB-mVenus from Arora et al., 2017
rpe_h2b_slbp.csv RPE/mCherry-SLBP:RPE cells expressing mCherry-SLBP and mTurq2-H2B reporters

All models included in the download:

fucci_rpe.xml FUCCI simulation model:Model of Cdt1 and geminin in U2OS cells
u2os_53bp1_p16_pcna.xml U20S Model 1:This SBML model represents U2OS cells expressing 53BP1, p16, and PCNA reporters
rpe_53bp1_p21.xml Model of RPE-1 cells:SBML model representing RPE-1 cells expressing reporters for 53BP1 and p21